Blood test to detect intracranial aneurysms and estimate risk in families
Official title: Testing a Blood-Based Assay for Detection and Risk Assessment of Intracranial Aneurysms in Familial Cases
Funded at Neurovascular Diagnostics, INC. · NIH-11417233 · Data updated 2026-11-12
A new blood test called AneuScreen+ aims to identify people at risk for brain aneurysms and predict rupture risk using a simple blood sample.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Neurovascular Diagnostics, INC. NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project start | September 16, 2025 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $266,097 |
| NIH project number | 5R43NS145909-02 |
| Project ID | NIH-11417233 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with a family history or higher risk of intracranial aneurysms who are candidates for screening or risk stratification.
✕Less likely to help
People without risk factors or aneurysms may not benefit from this specific blood test.
What this research studies
This project develops a blood-based biomarker assay to screen people, especially those with a family history, for intracranial aneurysms and to help doctors decide who needs imaging or treatment. It uses a non-invasive blood test to provide risk information that could guide monitoring or early intervention. The study will validate the test’s accuracy and usefulness in real-world clinical settings. If successful, the test could make screening more accessible and reduce sudden, life-threatening brain bleeds.
Why it matters
Potential benefit: If the test proves accurate, patients could be screened more easily to catch aneurysms early and personalize treatment decisions.
How similar studies have gone: Previous biomarker-based approaches have shown promise but require prospective validation in diverse populations.
Where this research is happening
-
Neurovascular Diagnostics, INC.
Buffalo, United States Active
Researchers
- Principal investigator: Poppenberg, Kerry — Neurovascular Diagnostics, INC.
- Study coordinator: Poppenberg, Kerry
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.