Blocking the movement of cells to prevent invasive prostate cancer

Preventing invasive prostate cancer

NIH-funded research University of Nebraska Medical Center · NIH-10931324

This study is testing a new treatment called KBU2046 that aims to stop prostate cancer from spreading by blocking the movement of cancer cells, and it's designed for anyone concerned about preventing invasive prostate cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Medical Center NIH-funded
Lab location1 site (Omaha, United States)
Project IDNIH-10931324 on NIH RePORTER

What this research studies

This research focuses on preventing invasive prostate cancer by inhibiting the movement of cancer cells. The team has developed a new agent called KBU2046, which selectively targets and inhibits cell motility, a key factor in the progression of cancer. Through a series of advanced studies, including biochemical and bioinformatics approaches, the researchers aim to identify how KBU2046 works at the molecular level and its potential to prevent the development of invasive cancer. This innovative approach could lead to new strategies for cancer interception and prevention.

Who could benefit from this research

Good fit: Ideal candidates for this research are men at high risk for developing prostate cancer, particularly those with early-stage disease.

Not a fit: Patients with advanced prostate cancer or those who have already been diagnosed with invasive cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of invasive prostate cancer, improving outcomes for patients.

How similar studies have performed: While the approach of selectively inhibiting cell motility is novel, similar strategies targeting cancer prevention have shown promise in other studies.

Where this research is happening

Omaha, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.