Blocking a key protein to reduce inflammation
Suppressing Inflammation by Blocking IKK Oligomer
This study is looking at how stopping a protein called IKK can help reduce inflammation, which is important for people dealing with autoimmune diseases and cancers, and the researchers want to find new ways to make this happen.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11007162 on NIH RePORTER |
What this research studies
This research investigates how blocking the IKK protein complex can help control inflammation, which is linked to various health issues like autoimmune diseases and cancers. The team aims to understand the activation process of IKK and how it contributes to inflammatory responses. By studying the interactions within the IKK complex, they hope to develop new strategies to inhibit its activity and reduce inflammation in affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with autoimmune diseases, chronic inflammation, or related conditions.
Not a fit: Patients with non-inflammatory conditions or those not affected by autoimmune diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for patients suffering from inflammatory diseases and autoimmune conditions.
How similar studies have performed: Previous research has shown promise in targeting similar pathways for inflammation control, suggesting potential for success in this approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Ghosh, Gourisankar — University of California, San Diego
- Study coordinator: Ghosh, Gourisankar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.