Biospecimen and pathology resource for colorectal cancer
Core B: Biospecimen and Pathology Core
Collecting and storing blood, tumor tissue, saliva, urine, and stool from people with colorectal cancer so researchers can better understand and reduce differences in cancer outcomes across populations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11176294 on NIH RePORTER |
What this research studies
This program collects samples such as blood, frozen and fixed tumor and normal tissue, saliva, urine, and stool from people with colorectal cancer at several partner hospitals. Samples are processed, reviewed by pathologists, tracked in a central system, and stored under standardized conditions, with some turned into tumor microarrays and digital images. The core performs DNA extraction and single-cell preparation and shares quality-controlled specimens with the SPORE projects and early-career investigators for biomarker and lab analyses. IRB approvals and institutional agreements are in place to protect privacy and enable approved sharing across sites.
Who could benefit from this research
Good fit: People diagnosed with colorectal cancer at participating hospitals who can consent to donate blood, tissue, saliva, urine, or stool for research.
Not a fit: People without colorectal cancer or those unwilling or unable to provide the required samples are unlikely to benefit directly from this core.
Why it matters
Potential benefit: Could speed development of better tests and treatments that address why colorectal cancer affects some groups more severely.
How similar studies have performed: Other biorepositories and pathology cores have successfully supported discovery of cancer biomarkers and informed treatment approaches, so this builds on proven methods.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Koehne, Amanda L — Fred Hutchinson Cancer Center
- Study coordinator: Koehne, Amanda L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.