Biospecimen and imaging collection for radiation-treated cancer patients

Core 2: Translational Biospecimens and Imaging Biomarkers

NIH-funded research Massachusetts General Hospital · NIH-11184401

This project collects blood, tissue, and imaging samples from people receiving radiation therapy so researchers can use them to personalize cancer care.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11184401 on NIH RePORTER

What this research studies

You would be asked to give permission for your blood, tissue, and medical images to be collected and securely stored using standardized procedures. The core coordinates sample processing and links those samples to your clinical information while protecting your identity. Samples and imaging from patients at Massachusetts General Hospital and MD Anderson are shared with approved researchers to study markers related to radiation treatment. The goal is to help researchers develop imaging and blood markers that could guide safer, more effective radiation plans over time.

Who could benefit from this research

Good fit: Patients who are receiving or being evaluated for radiation therapy at the participating centers and who can give informed consent to donate blood, tissue, and imaging data are the intended participants.

Not a fit: People not receiving radiation therapy, unwilling to donate samples, or treated at centers outside the participating sites are unlikely to directly benefit from this core activity.

Why it matters

Potential benefit: If successful, this effort could help doctors tailor radiation therapy using blood and imaging markers to improve outcomes and reduce side effects.

How similar studies have performed: Previous biomarker and imaging collection efforts have shown promise in guiding cancer care, but standardizing and sharing biospecimens across centers specifically for personalizing radiotherapy is still an emerging approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.