Biomedical research facility to accelerate human-relevant disease research
Official title: Biomedical Research Facility for the Translational Hub for Research, Innovation, Validation, and Excellence (THRIVE)
Funded at Southern Research Institute · NIH-11523327 · Data updated 2026-11-12
A new shared-use hub called THRIVE will give researchers easier access to human-relevant models and workflows to speed translational science.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Southern Research Institute NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project start | September 18, 2026 |
| Project end | November 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $8,000,000 |
| NIH project number | 1C06OD042705-01 |
| Project ID | NIH-11523327 on NIH RePORTER |
Who could benefit from this research
✓Could help
Researchers and clinicians who study human diseases could benefit indirectly through faster translation of findings into patient care; patients may benefit from more reliable and human-relevant preclinical data.
✕Less likely to help
Direct patient participation is not described; this grant focuses on building infrastructure and capabilities.
What this research studies
THRIVE is a purpose-built facility designed to expand access to new approaches and validated human-relevant model systems. It brings together workflows, pathology, analytics, and data resources in a single, shared environment to improve reproducibility and interpretation of results. Investigators will be able to select and compare different models, refine methods, and use advanced systems within a networked core to accelerate translation from basic science to clinical research.
Why it matters
Potential benefit: If successful, THRIVE could streamline how scientists test human-relevant models and accelerate the development of therapies and diagnostics.
How similar studies have gone: This is a facility-driven platform with precedent in shared-core and translational research initiatives that have improved collaboration and data quality.
Where this research is happening
-
Southern Research Institute
Birmingham, United States Active
Researchers
- Principal investigator: Ledebur, Harry — Southern Research Institute
- Study coordinator: Ledebur, Harry
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.