NIH-funded research NIH-funded research

Biomedical research facility to accelerate human-relevant disease research

Official title: Biomedical Research Facility for the Translational Hub for Research, Innovation, Validation, and Excellence (THRIVE)

Funded at Southern Research Institute · NIH-11523327 · Data updated 2026-11-12

A new shared-use hub called THRIVE will give researchers easier access to human-relevant models and workflows to speed translational science.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSouthern Research Institute
NIH-funded
Lab location1 site (Birmingham, United States)
Project startSeptember 18, 2026
Project endNovember 30, 2030
Funding year2026
Award (this year)$8,000,000
NIH project number1C06OD042705-01
Project IDNIH-11523327 on NIH RePORTER

Who could benefit from this research

Could help

Researchers and clinicians who study human diseases could benefit indirectly through faster translation of findings into patient care; patients may benefit from more reliable and human-relevant preclinical data.

Less likely to help

Direct patient participation is not described; this grant focuses on building infrastructure and capabilities.

What this research studies

THRIVE is a purpose-built facility designed to expand access to new approaches and validated human-relevant model systems. It brings together workflows, pathology, analytics, and data resources in a single, shared environment to improve reproducibility and interpretation of results. Investigators will be able to select and compare different models, refine methods, and use advanced systems within a networked core to accelerate translation from basic science to clinical research.

Why it matters

Potential benefit: If successful, THRIVE could streamline how scientists test human-relevant models and accelerate the development of therapies and diagnostics.

How similar studies have gone: This is a facility-driven platform with precedent in shared-core and translational research initiatives that have improved collaboration and data quality.

Where this research is happening

  • Southern Research Institute
    Birmingham, United States
    Active

Researchers

  • Principal investigator: Ledebur, Harry — Southern Research Institute
  • Study coordinator: Ledebur, Harry

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.