Biomarkers of flavonoid intake and metabolic risk
Official title: Biomarkers of Dietary Flavonoid Intake, Carbonyl Stress, and Metabolic Risk
Funded at North Carolina Agri & Tech St Univ · NIH-11367372 · Data updated 2026-11-12
A study to find biological markers of how flavonoid-rich foods affect carbon stress and metabolic health in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina Agri & Tech St Univ NIH-funded |
| Lab location | 1 site (Greensboro, United States) |
| Project start | August 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $664,297 |
| NIH project number | 5R01DK131753-04 |
| Project ID | NIH-11367372 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults at risk for metabolic disorders who consume flavonoid-rich foods and provide biological samples.
✕Less likely to help
Individuals without dietary exposure to flavonoids or without interest in metabolic health biomarkers may not benefit.
What this research studies
This project looks for measurable biomarkers that reflect how flavonoids from plant foods influence metabolic risk, aiming to improve how we track diet and disease risk. Researchers will examine how flavonoids interact with reactive carbonyl species and whether these interactions relate to diabetes and heart disease risk. The work combines dietary data, biological samples, and genetic/microbiome considerations to understand individual differences in response. Results could lead to better tools for personalized nutrition guidance and disease prevention.
Why it matters
Potential benefit: If successful, this research could yield reliable biomarkers to monitor flavonoid intake and its impact on metabolic health, guiding personalized dietary recommendations.
How similar studies have gone: Previous work shows flavonoids can interact with oxidative stress pathways, but validated biomarkers for flavonoid intake remain limited.
Where this research is happening
-
North Carolina Agri & Tech St Univ
Greensboro, United States Active
Researchers
- Principal investigator: Sang, Shengmin — North Carolina Agri & Tech St Univ
- Study coordinator: Sang, Shengmin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.