Biomarkers in Type 1 Diabetes risk and progression for people at risk
Official title: The KQ1 serum study: soluble biomarkers for T1D risk, development & progression
Funded at University of Miami School of Medicine · NIH-11510180 · Data updated 2026-11-12
A study to identify blood biomarkers that help predict who will develop or progress in Type 1 diabetes among people at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,215,279 |
| NIH project number | 7R01DK138369-03 |
| Project ID | NIH-11510180 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals at risk for Type 1 diabetes, particularly those with multiple autoantibodies.
✕Less likely to help
People not at risk or not progressing to diabetes during the study period may not benefit.
What this research studies
This project studies blood serum and immune markers to understand how Type 1 diabetes begins and changes over time. It analyzes samples from individuals who are at risk, comparing those who progress to diabetes with those who do not over three years. The goal is to find reliable biomarkers that can improve risk stratification and guide future prevention strategies.
Why it matters
Potential benefit: If successful, personalized risk profiles could lead to earlier prevention efforts and targeted therapies for people at risk of Type 1 diabetes.
How similar studies have gone: Previous biomarker studies in at-risk individuals have identified candidate markers, but validation in larger cohorts is needed.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Homann, Dirk — University of Miami School of Medicine
- Study coordinator: Homann, Dirk
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.