Biomarkers and timing cues for body clocks in people
Official title: Biomarkers for Peripheral Circadian Clocks in Humans
Funded at University of Colorado · NIH-11406027 · Data updated 2026-11-12
A seven-week study will explore how time cues affect body clocks outside the brain and look for new markers that show how these clocks work in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project start | September 1, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $666,859 |
| NIH project number | 5R01HL165343-04 |
| Project ID | NIH-11406027 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults willing to participate in a crossover trial and provide samples to study circadian biomarkers.
✕Less likely to help
Individuals not interested in participating in a multi-week clock study or providing samples may not benefit.
What this research studies
This study will enroll adults to participate in a seven-week, randomized, crossover trial focused on peripheral circadian rhythms in humans. Participants will receive different time cues to see how they influence rhythm markers in tissues and blood, helping to map how body clocks align with daily patterns. Researchers will collect blood and possibly tissue samples to identify biomarkers that reflect peripheral clock activity and response to zeitgebers, with findings guiding future circadian-based therapies.
Why it matters
Potential benefit: If successful, this work could lead to new ways to align body clocks, potentially improving sleep, metabolism, and overall health.
How similar studies have gone: Previous circadian research has shown promising biomarker and timing cue findings, but this project aims to extend those discoveries in humans.
Where this research is happening
-
University of Colorado
Boulder, United States Active
Researchers
- Principal investigator: Wright, Kenneth P — University of Colorado
- Study coordinator: Wright, Kenneth P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.