NIH-funded research R01 grant

Bilingualism and language resilience in Hispanic adults with primary progressive aphasia

Official title: Bilingual Factors Associated with Cognitive Reserve and Linguistic Resilience in Hispanics with Primary Progressive Aphasia

Funded at University of Texas at Austin · NIH-11285140 · Data updated 2026-11-12

This project will learn how different bilingual experiences affect thinking and language skills in Hispanic adults with primary progressive aphasia.

More Resilience research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas at Austin
NIH-funded
Lab location1 site (Austin, United States)
Project startDecember 1, 2022
Project endNovember 30, 2027
Funding year2026
Award (this year)$468,205
NIH project number5R01AG080470-04
Project IDNIH-11285140 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are Hispanic adults diagnosed with primary progressive aphasia who speak more than one language (for example, Spanish and English).

Less likely to help

People who are monolingual, do not have primary progressive aphasia, or whose language background is not Hispanic/Latinx may not be eligible or directly benefit from this project.

What this research studies

Researchers will collect detailed language histories (which language you learned first, how well you speak each language, how often you use them, and when you learned them) and give standardized tests of thinking and language across different language areas. They will compare how a person’s first and second languages change over time in people with primary progressive aphasia to find patterns of resilience or decline. The team is focusing on Hispanic individuals to reflect sociocultural and linguistic differences that past studies often missed. Other factors such as age and education will be considered to help separate bilingual effects from other influences on thinking and language.

Why it matters

Potential benefit: If successful, this work could help predict which language will stay stronger and guide more personalized communication therapies for bilingual people with PPA.

How similar studies have gone: Previous research has suggested bilingualism can delay dementia in some cases, but results are mixed and studies specifically on bilingual primary progressive aphasia in Hispanic groups are limited.

Where this research is happening

  • University of Texas at Austin
    Austin, United States
    Active

Researchers

  • Principal investigator: Grasso, Stephanie M — University of Texas at Austin
  • Study coordinator: Grasso, Stephanie M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.