NIH-funded research R01 grant

Bilateral hearing: how the two ears combine to understand sound

Official title: Bilateral integration of the auditory scene

Funded at Louisiana State Univ A&m Col Baton Rouge · NIH-11353895 · Data updated 2026-11-12

Scientists are studying how the brain combines information from both ears to tell whether a sound comes from one source or multiple sources, which could help people with hearing difficulties.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLouisiana State Univ A&m Col Baton Rouge
NIH-funded
Lab location1 site (Baton Rouge, United States)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$361,649
NIH project number5R01DC019348-05
Project IDNIH-11353895 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are individuals with auditory processing challenges or tinnitus who could benefit from improved understanding of bilateral sound processing.

Less likely to help

The research is focused on basic brain mechanisms; direct benefit to any single patient in the short term is not guaranteed.

What this research studies

This grant explores how the brain’s auditory system binds bilateral sound signals to create a coherent perception of complex environments. Researchers will look at neural pathways between the inferior colliculus and the contralateral medial geniculate body to understand how two ears work together. The work aims to map how excitatory and inhibitory signals coordinate across the two sides of the brain to support accurate sound localization and recognition. Findings could shed light on conditions like tinnitus and central auditory processing disorders and inform new approaches to hearing health. The project is conducted at Louisiana State University with a focus on human-relevant brain mechanisms involved in auditory integration.

Why it matters

Potential benefit: If successful, findings could lead to better diagnostics and therapies for people with hearing disorders and difficulties processing sounds from both ears.

How similar studies have gone: Previous work supports that bilateral auditory pathways contribute to sound integration, but the specific commissural projection system studied here is less explored and represents a novel direction.

Where this research is happening

  • Louisiana State Univ A&m Col Baton Rouge
    Baton Rouge, United States
    Active

Researchers

  • Principal investigator: Lee, Charles C — Louisiana State Univ A&m Col Baton Rouge
  • Study coordinator: Lee, Charles C

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.