Big South/West NIDA center for improving care for stimulant and other substance use
NIDA Clinical Trials Network: Big South/West Node
This program runs clinical research testing new medications and care approaches for adults with stimulant and other substance use problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11261092 on NIH RePORTER |
What this research studies
This center runs and supports multisite clinical research trials across hospitals and clinics to find better treatments for people with stimulant or other substance use disorders. The team leads randomized medication trials and also tests ways to deliver care, such as universal screening, measurement-based buprenorphine care, and remote methadone monitoring. The node builds on prior large trials (including the ADAPT-2 methamphetamine medication trial) and partners with clinics across the Big South/West region to recruit and follow patients.
Who could benefit from this research
Good fit: Adults with stimulant use disorder (including methamphetamine) and people receiving medications for opioid use disorder at participating clinics would be the most likely candidates.
Not a fit: People under 21, those without a substance use disorder, or anyone seeking immediate individual clinical care rather than research participation are unlikely to benefit directly from joining this program.
Why it matters
Potential benefit: If successful, this work could bring effective medications and better ways to deliver treatment to people with stimulant and other substance use disorders.
How similar studies have performed: Previous CTN work such as the ADAPT-2 trial has produced publications and early leads, but effective medications for stimulant use remain limited so this builds on partial successes and new approaches.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Trivedi, Madhukar H. — Ut Southwestern Medical Center
- Study coordinator: Trivedi, Madhukar H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.