BIDMC data and tissue center for lupus kidney disease
Core C- BIDMC Core
Creating fast, high-quality single-cell and tissue data from kidney and blood samples to help researchers better understand and treat lupus nephritis.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11324182 on NIH RePORTER |
What this research studies
From a patient's perspective, this core collects and processes kidney and blood samples from people with lupus nephritis and uses automated single-cell and spatial profiling to map the cells and molecules in diseased tissue. The team builds standardized pipelines for data generation, quality control, and secure tracking so results are reliable and usable by many researchers. Staff deliver processed data, code, and detailed metadata following FAIR principles so different studies can be combined and compared. These activities support the program's projects by speeding data delivery and making it easier to find new diagnostic markers or treatment targets.
Who could benefit from this research
Good fit: People with lupus nephritis who are undergoing kidney biopsies or willing to donate blood or tissue samples for research are the most relevant participants.
Not a fit: If you do not have lupus nephritis or cannot/will not provide tissue or blood samples, you would not be eligible to participate and would not directly benefit from this core.
Why it matters
Potential benefit: Could speed discovery of better diagnostics and treatments for lupus nephritis by giving researchers clearer, standardized maps of diseased kidneys.
How similar studies have performed: Single-cell and spatial profiling have already produced important insights in kidney and other diseases, although building automated, production-grade pipelines with full data provenance is a newer effort.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Vlachos, Ioannis — Beth Israel Deaconess Medical Center
- Study coordinator: Vlachos, Ioannis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.