Better Ways to Understand Thinking Skills in Children with Down Syndrome

Cognitive Outcome Measures in School Age Children with Down Syndrome (ECODS)

NIH-funded research Cincinnati Childrens Hosp Med Ctr · NIH-11195157

This project aims to create more accurate and reliable ways to track changes in thinking and learning abilities for children with Down syndrome.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-11195157 on NIH RePORTER

What this research studies

For children with Down syndrome, it's hard to know if new treatments are working because we don't have good tools to measure changes in their thinking skills. This project is developing and testing new methods to understand how these skills change over time. We are looking at different ways to assess thinking, like verbal tasks, nonverbal puzzles, computer activities, and parent reports. The goal is to find the best tools that can reliably show improvements or changes in a child's cognitive abilities.

Who could benefit from this research

Good fit: This research is focused on school-age children with Down syndrome, typically between 0 and 20 years old.

Not a fit: Patients who are not within the school-age range or do not have Down syndrome would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work will provide essential tools for future clinical efforts, helping researchers determine if new medications or therapies are truly helping children with Down syndrome.

How similar studies have performed: This project builds upon prior work that began evaluating promising measures, with multi-site studies being the next crucial step to support new interventions.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.