Better ways to see and treat aggressive prostate cancer

Enhanced imaging and treatment of aggressive subtypes of prostate cancer

NIH-funded research Ut Southwestern Medical Center · NIH-11161619

This work aims to improve how we find and treat aggressive prostate cancer using special imaging and targeted therapies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-11161619 on NIH RePORTER

What this research studies

We are exploring new ways to detect and treat prostate cancer by focusing on a specific marker called PSMA, which is often found in high amounts on cancer cells. Our goal is to refine existing PSMA-targeted imaging techniques, like PET scans, to make them even more effective for patients. We are also developing new, highly sensitive imaging methods, such as photoacoustic imaging, to better understand primary tumors and identify aggressive forms of the disease. This will help us distinguish aggressive cancers from those that are less harmful, leading to more precise care.

Who could benefit from this research

Good fit: This research is most relevant for patients diagnosed with or at risk for aggressive subtypes of prostate cancer.

Not a fit: Patients with prostate cancer that does not express PSMA or those with very early, non-aggressive forms of the disease may not directly benefit from these specific approaches.

Why it matters

Potential benefit: If successful, this work could lead to earlier and more accurate detection of aggressive prostate cancer, allowing for more effective and personalized treatment plans.

How similar studies have performed: Targeting PSMA for prostate cancer imaging and therapy has already shown significant success in nuclear medicine, and this work builds upon that foundation.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.