Better Understanding and Predicting Outcomes for Lung Blood Clots Using CT Scans

Classification and Prognostication in Pulmonary Thromboembolism Using Computed Tomography Image Analytics

NIH-funded research Brigham and Women's Hospital · NIH-11145622

This project uses advanced CT scan analysis to help doctors better understand and predict how lung blood clots affect patients over time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11145622 on NIH RePORTER

What this research studies

Lung blood clots, also known as pulmonary embolism, can have lasting effects, sometimes leading to chronic conditions like CTEPH or ongoing breathlessness. It's often hard to tell early on who might develop these long-term problems or if a patient already has a chronic form of the disease. This project aims to develop new ways to analyze CT scans, which are a common tool for diagnosing lung clots. By using advanced computer methods, we hope to get a clearer picture of the disease's path for each patient. This could help doctors make more informed decisions about treatment and follow-up care.

Who could benefit from this research

Good fit: This research focuses on patients who have experienced or are at risk for pulmonary thromboembolism, including those with acute lung blood clots or chronic conditions like CTEPH.

Not a fit: Patients without a history of or risk for pulmonary thromboembolism would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could help doctors identify patients at risk for long-term complications from lung blood clots earlier, leading to more personalized and effective treatment plans.

How similar studies have performed: While CT imaging is standard, this project explores novel quantitative methods for image analysis to improve prognostication, building on existing knowledge but pushing new boundaries.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.