Better Understanding and Predicting Outcomes for Lung Blood Clots Using CT Scans
Official title: Classification and Prognostication in Pulmonary Thromboembolism Using Computed Tomography Image Analytics
Funded at Brigham and Women's Hospital · NIH-11145622 · Data updated 2026-11-12
This project uses advanced CT scan analysis to help doctors better understand and predict how lung blood clots affect patients over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $757,154 |
| NIH project number | 5R01HL164717-04 |
| Project ID | NIH-11145622 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research focuses on patients who have experienced or are at risk for pulmonary thromboembolism, including those with acute lung blood clots or chronic conditions like CTEPH.
✕Less likely to help
Patients without a history of or risk for pulmonary thromboembolism would not directly benefit from this specific research.
What this research studies
Lung blood clots, also known as pulmonary embolism, can have lasting effects, sometimes leading to chronic conditions like CTEPH or ongoing breathlessness. It's often hard to tell early on who might develop these long-term problems or if a patient already has a chronic form of the disease. This project aims to develop new ways to analyze CT scans, which are a common tool for diagnosing lung clots. By using advanced computer methods, we hope to get a clearer picture of the disease's path for each patient. This could help doctors make more informed decisions about treatment and follow-up care.
Why it matters
Potential benefit: If successful, this work could help doctors identify patients at risk for long-term complications from lung blood clots earlier, leading to more personalized and effective treatment plans.
How similar studies have gone: While CT imaging is standard, this project explores novel quantitative methods for image analysis to improve prognostication, building on existing knowledge but pushing new boundaries.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Rahaghi, Farbod Nicholas — Brigham and Women's Hospital
- Study coordinator: Rahaghi, Farbod Nicholas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.