Better ultrasound checks to find cancer in lymph nodes
In vivo Evaluation of Lymph Nodes Using Quantitative Ultrasound
This project uses a special type of ultrasound during biopsies to help tell if lymph nodes in people with breast cancer have cancer spread or are benign.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11262613 on NIH RePORTER |
What this research studies
If you have breast cancer and are having an ultrasound-guided lymph node biopsy, researchers will capture extra echo-signal data with the usual clinical scanner. They will apply quantitative‑ultrasound methods to look for patterns that indicate metastasis versus lymphoma or benign changes. The supplement expands the work to multiple Weill Cornell clinical sites so the findings apply to patients from different neighborhoods and socio-economic groups. Researchers will link patients' zip code data to public area-level information to understand how local factors relate to test performance.
Who could benefit from this research
Good fit: Ideal candidates are people with breast cancer who are undergoing medically required ultrasound-guided lymph node biopsies at participating Weill Cornell sites.
Not a fit: People without breast cancer, those not having ultrasound-guided lymph node biopsies, or patients treated outside the participating sites are unlikely to benefit directly from this work.
Why it matters
Potential benefit: If successful, this could help doctors detect lymph node metastases more accurately during routine scans, enabling faster and more precise staging and treatment decisions.
How similar studies have performed: Previous pilot work by the same teams produced encouraging results using quantitative ultrasound to detect lymph node metastases, but wider testing with standard clinical scanners is still underway.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Mamou, Jonathan — Weill Medical Coll of Cornell Univ
- Study coordinator: Mamou, Jonathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.