Better treatments for advanced solid tumors
Cancer Therapeutics Program
Testing new drug combinations and biomarkers to help adults with advanced solid tumors such as lung, prostate, pancreas, and melanoma.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11469220 on NIH RePORTER |
What this research studies
This program turns laboratory findings into early- and late-phase clinical trials aimed at improving care for people with advanced solid tumors. Teams at the Abramson Cancer Center run Phase I, II, and III trials while developing biomarkers to improve safety and guide which patients receive which treatments. The program combines basic, translational, and clinical research and works with community outreach to address cancer needs in their catchment area. Research includes lab studies, biomarker development, and human trials that directly connect scientific discoveries to patient care.
Who could benefit from this research
Good fit: Adults with advanced or treatment-resistant solid tumors (for example lung, prostate, pancreas, or melanoma) who meet trial eligibility and can receive care at the Abramson Cancer Center.
Not a fit: People with early-stage cancers, non-solid tumors, or those who cannot travel to or meet eligibility requirements at the Philadelphia site are unlikely to benefit directly from this program.
Why it matters
Potential benefit: Could lead to safer, more effective, and more personalized therapies for people with advanced solid tumors.
How similar studies have performed: Some targeted therapies and biomarker-guided approaches have improved outcomes in certain cancers, but many new combinations and biomarkers remain experimental and unproven.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Reiss Binder, Kim a — University of Pennsylvania
- Study coordinator: Reiss Binder, Kim a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.