Better Tests for Prostate Cancer Management
BCC for Prostate Cancer: Discovery and Translation of Biomarkers for Clinical Unmet Needs
This work aims to create new blood tests to help men with low-risk prostate cancer make better decisions about their treatment and follow-up care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11111406 on NIH RePORTER |
What this research studies
Many men with low-risk prostate cancer choose active surveillance, which means closely watching the cancer instead of immediate treatment. However, it's currently hard to know for sure who truly has low-risk cancer and who might need treatment later. This project is developing new tests that combine several biological markers to give a clearer picture of a man's prostate cancer. These tests will help doctors decide if active surveillance is the right choice and identify when the cancer might be becoming more aggressive. The goal is to reduce unnecessary treatments for some men while ensuring others receive timely care.
Who could benefit from this research
Good fit: Ideal candidates are men diagnosed with low-risk prostate cancer who are considering or currently undergoing active surveillance.
Not a fit: Patients with high-risk or advanced prostate cancer may not directly benefit from these specific tests, as they are focused on early assessment and monitoring of low-risk disease.
Why it matters
Potential benefit: If successful, these new tests could help men with prostate cancer avoid unnecessary biopsies and treatments, while also ensuring those who need intervention receive it promptly.
How similar studies have performed: While individual biomarkers have been explored, this project focuses on developing novel combined biomarker tests (IVDMIA) for improved accuracy in prostate cancer management.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Chan, Daniel Wanyui — Johns Hopkins University
- Study coordinator: Chan, Daniel Wanyui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.