Better symptom care for adults with cystic fibrosis
Advancing Symptom Science and Management in Cystic Fibrosis: Biological, Social, and Clinical Mechanisms
['FUNDING_R01'] · EMORY UNIVERSITY · NIH-11233266
This project looks at how biological markers, life circumstances, and care experiences relate to symptoms like pain, breathlessness, and fatigue in adults with cystic fibrosis.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11233266 on ClinicalTrials.gov |
What this research studies
If you join, you would complete surveys about your symptoms and experiences and may take part in an interview about your care. Researchers will collect blood and exhaled breath condensate to measure metabolic markers linked to inflammation and oxidative stress. They will group co-occurring symptoms to find common symptom patterns and link those patterns to social factors and metabolic signatures. The combined findings aim to paint a clearer, person-centered picture of why symptoms happen and how care might be improved.
Who could benefit from this research
Good fit: Adults aged 21 and older living with cystic fibrosis who can complete surveys, provide blood and breath samples, and participate in interviews are ideal candidates.
Not a fit: People under 21, those unable or unwilling to provide samples or complete surveys/interviews, or those not receiving care at participating sites likely would not be included and would not directly benefit.
Why it matters
Potential benefit: If successful, the work could help tailor symptom management and improve quality of life for adults with cystic fibrosis.
How similar studies have performed: Previous studies have linked metabolic markers to lung inflammation and shown social factors affect outcomes, but combining symptom clusters, untargeted metabolomics, and patient interviews is a newer and less-tested approach.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KAVALIERATOS, DIONYSIOS — EMORY UNIVERSITY
- Study coordinator: KAVALIERATOS, DIONYSIOS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.