Better Swelling Control After Knee Replacement Surgery
Swelling Management after Total Knee Arthroplasty
['FUNDING_R21'] · UNIVERSITY OF COLORADO DENVER · NIH-11143164
This project is exploring if a special compression garment can help reduce swelling and improve recovery for people who have had total knee replacement surgery.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11143164 on ClinicalTrials.gov |
What this research studies
After total knee replacement surgery, many people experience significant swelling, which can make it harder to regain strength and function, potentially leading to long-term weakness. While standard compression stockings offer limited help, our team has developed an adjustable compression garment that showed promising results in a small initial test, cutting swelling by half. This project aims to carefully examine how effective this new garment is at reducing swelling and improving muscle strength and overall recovery. We also want to understand the direct connection between swelling and how well your leg muscles work after surgery.
Who could benefit from this research
Good fit: Ideal candidates would be individuals preparing for or recently undergoing total knee replacement surgery for osteoarthritis.
Not a fit: Patients who have not had or are not planning to have total knee replacement surgery would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this new garment could lead to faster recovery, better strength, and improved long-term outcomes for patients undergoing total knee replacement.
How similar studies have performed: A preliminary study by this team showed that the inelastic, adjustable compression garment decreased early postoperative swelling by 50%, suggesting a promising approach.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BADE, MICHAEL J — UNIVERSITY OF COLORADO DENVER
- Study coordinator: BADE, MICHAEL J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.