Better STI screening for people using PrEP
STI Response and Recommendations Under PrEP (STIRRUP)
This project combines large datasets and mathematical models to find improved ways to detect and treat gonorrhea, chlamydia, and syphilis in people taking PrEP, especially men who have sex with men.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11371344 on NIH RePORTER |
What this research studies
You would hear about efforts that use health records, testing data, and other big data streams combined with mathematical and economic models to design smarter STI screening tied to PrEP care. The team will examine where and for whom current screening falls short, looking at differences by age, race, geography, and clinic setting. Models will simulate how different screening schedules and clinic practices affect STI detection, treatment, and onward transmission. The goal is to recommend screening approaches that fit real-world clinics and reduce untreated, often-asymptomatic infections among PrEP users.
Who could benefit from this research
Good fit: Ideal candidates are people who use PrEP—particularly men who have sex with men and groups with higher STI burdens—who receive care at clinics participating in the project or whose clinic data are included in the analyses.
Not a fit: People not on PrEP, those whose clinics do not participate or share data, and individuals at very low STI risk are unlikely to directly benefit from this project.
Why it matters
Potential benefit: If successful, this work could lead to more timely STI detection and treatment for people on PrEP, lowering infections and health disparities.
How similar studies have performed: Routine STI screening linked to PrEP care has shown benefit in other work, but combining large-scale data with economic and mathematical optimization to set screening policies is a newer approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Jenness, Samuel — Emory University
- Study coordinator: Jenness, Samuel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.