Better sleep and body‑clock timing to lower heart and metabolic risk in teens with type 1 diabetes
Mechanisms underlying the relationship between sleep health and circadian timing with cardiometabolic risk in adolescents with type 1 diabetes
This project will try improving sleep and daily body‑clock timing in 12–20 year olds with type 1 diabetes to reduce early heart and metabolic problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11176230 on NIH RePORTER |
What this research studies
You would join a program that combines behavior changes (like more regular bedtimes) and timed physiological cues to help you sleep longer and shift your internal clock earlier. The team will monitor your sleep with wearable devices and collect health measures such as blood pressure, blood sugars, and other metabolic markers before and after the intervention. They will also study biological signals to understand how sleep and circadian timing affect heart and metabolic risk in teens with type 1 diabetes. The same combined approach improved sleep timing and duration in teens without type 1 diabetes, and this project applies it to adolescents who have T1D.
Who could benefit from this research
Good fit: Ideal candidates are 12–20 year olds who have type 1 diabetes and are willing to follow sleep‑timing recommendations and attend study visits and monitoring.
Not a fit: Children under 12, adults, people without type 1 diabetes, or those unable/unwilling to follow the sleep intervention or attend in‑person testing are unlikely to benefit directly from participation.
Why it matters
Potential benefit: If successful, this could reduce early cardiovascular and metabolic risk in adolescents with type 1 diabetes by improving sleep and circadian timing.
How similar studies have performed: Related interventions have improved sleep duration and shifted circadian timing in teens without type 1 diabetes, but applying this combined approach and studying the physiological mechanisms is new for adolescents with T1D.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Simon, Stacey Lynn — University of Colorado Denver
- Study coordinator: Simon, Stacey Lynn
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.