Better skin cancer surgery guidance

Multimodal confocal microscopy for surgical guidance of skin resections

['FUNDING_R01'] · UNIVERSITY OF TEXAS AT AUSTIN · NIH-11136501

This project aims to create a faster and more accessible way to guide skin cancer surgery, especially for people in areas with limited medical resources.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF TEXAS AT AUSTIN (nih funded)
Locations1 site (AUSTIN, UNITED STATES)
Trial IDNIH-11136501 on ClinicalTrials.gov

What this research studies

Mohs surgery is very effective for nonmelanoma skin cancer, but it can be long and expensive due to the need for immediate lab analysis during the procedure. We are working on a new approach called "optical Mohs" that uses a special microscope and computer learning to quickly identify cancer cells in freshly removed skin. This method could make Mohs surgery more available and less costly, particularly for patients in rural or underserved communities. Our goal is to develop an automated tool that provides accurate results without needing a pathologist to read every image, making the process much quicker.

Who could benefit from this research

Good fit: This research is ultimately intended to benefit patients with nonmelanoma skin cancer who are candidates for Mohs surgery, especially those in areas with limited access to specialized care.

Not a fit: Patients without nonmelanoma skin cancer or those not requiring surgical removal of skin lesions would not directly benefit from this specific technology.

Why it matters

Potential benefit: If successful, this technology could make highly effective skin cancer surgery more accessible, faster, and potentially less expensive for many patients.

How similar studies have performed: Previous work has shown that similar microscopy techniques can produce images comparable to traditional lab methods, but this project is novel in combining multiple microscopy types with machine learning for automated, highly accurate diagnosis.

Where this research is happening

AUSTIN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.