Better PrEP access and support for Black cisgender women

RFA-PS-23-001 - Project PrOVIDE: PrEP Optimization Via Implementation, Dissemination, and Evaluation

NIH-funded research Lurie Children's Hospital of Chicago · NIH-11140949

This project will try ways to help Black cisgender women learn about, start, and keep using PrEP to prevent HIV.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionLurie Children's Hospital of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11140949 on NIH RePORTER

What this research studies

If you join, clinics in six U.S. counties will roll out combined supports like routine PrEP education, standardized provider training, electronic medical record prompts, PrEP navigation, clinical champions, and mobile health tools. The team will adapt which strategies are used in each clinic through local planning and then track who hears about PrEP, who starts it, and who stays on it. Researchers will use implementation science methods to measure how well the approaches work and which supports patients find most useful. The work builds on earlier interviews and surveys that identified specific barriers for Black cisgender women and aims to make clinic care easier to use.

Who could benefit from this research

Good fit: Black cisgender women at risk for HIV who receive care or live in the participating clinics or counties are the ideal candidates.

Not a fit: People who live outside the participating counties, are not at risk for HIV, or are already stably on PrEP may not receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this could increase PrEP knowledge, starts, and long-term use among Black cisgender women and help reduce new HIV infections.

How similar studies have performed: Similar implementation approaches have improved PrEP uptake among men who have sex with men and transgender women, but they are less tested for Black cisgender women.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.