Better pain relief with less risk of opioid abuse
Deterrents for prescription opioid abuse
['FUNDING_R01'] · UNIVERSITY OF MISSISSIPPI MED CTR · NIH-11081630
This project looks for new ways to combine pain medications to make them more effective and less likely to be misused.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MISSISSIPPI MED CTR (nih funded) |
| Locations | 1 site (JACKSON, UNITED STATES) |
| Trial ID | NIH-11081630 on ClinicalTrials.gov |
What this research studies
Prescription opioids are very good at treating severe pain, but they also carry a high risk of misuse and overdose. Our work explores combining these powerful pain relievers with other medications that might reduce their addictive potential. We are focusing on new types of medications that could offer pain relief without the typical side effects often seen with similar drugs. The goal is to find safer ways to manage pain while also preventing the serious public health issues associated with opioid misuse.
Who could benefit from this research
Good fit: Patients experiencing moderate to severe acute pain who require opioid medication and are concerned about its potential for misuse might benefit from future treatments developed from this research.
Not a fit: Patients who do not experience pain requiring opioid medication or those seeking non-pharmacological pain management may not directly benefit from this specific medication-focused research.
Why it matters
Potential benefit: This work could lead to new pain medications that are both highly effective and significantly safer, reducing the risk of addiction and overdose for patients.
How similar studies have performed: Previous work in this program has shown promising results by combining different types of opioid-related medications to reduce abuse-related effects and enhance pain relief.
Where this research is happening
JACKSON, UNITED STATES
- UNIVERSITY OF MISSISSIPPI MED CTR — JACKSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FREEMAN, KEVIN B. — UNIVERSITY OF MISSISSIPPI MED CTR
- Study coordinator: FREEMAN, KEVIN B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.