Better pain care for people with knee osteoarthritis and other health conditions
Official title: Optimizing the value of pain management in knee OA patients with comorbidities
Funded at Brigham and Women's Hospital · NIH-11325440 · Data updated 2026-11-12
This project looks at ways to make pain care more effective, affordable, and easier to access for people with knee osteoarthritis who also have other medical problems.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2018 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $679,279 |
| NIH project number | 5R01AR074290-08 |
| Project ID | NIH-11325440 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults with symptomatic knee osteoarthritis, including those who have other chronic health conditions or live in rural or low-resource settings.
✕Less likely to help
People without knee osteoarthritis or those whose pain is already well controlled by current care are unlikely to see direct benefits from this project.
What this research studies
Researchers will analyze large patient records and real-world care patterns to see which pain treatments work best and cost least for people like me who have knee osteoarthritis and other health issues. They will compare exercise programs, telemedicine visits, injections into the knee, and the move of some knee surgeries to outpatient settings. The team will also study how insurance, education, and living in rural or low-resource areas change access and outcomes. Computer models and cohort analyses will be used to produce practical recommendations for doctors and policymakers.
Why it matters
Potential benefit: If successful, this work could lead to clearer guidance that helps people with knee OA get more effective, lower-cost, and more accessible pain care.
How similar studies have gone: Prior research supports exercise and some telemedicine approaches but questions remain about the effectiveness and cost of many intraarticular injections, so this work builds on existing evidence while addressing gaps.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Losina, Elena — Brigham and Women's Hospital
- Study coordinator: Losina, Elena
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.