Better online support for sexual problems after breast cancer

Optimizing psychosocial intervention for breast cancer-related sexual morbidity: A factorial trial using the National Cancer Institute Community Oncology Research Program (NCORP) network

NIH-funded research University of Virginia · NIH-11239818

This project tests which parts of an online program help partnered breast cancer survivors reduce sexual distress while keeping the program easy to use.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia NIH-funded
Lab location1 site (Charlottesville, United States)
Project IDNIH-11239818 on NIH RePORTER

What this research studies

You would be invited to join an online program if you're an intimately partnered woman who finished your main breast cancer treatment and are having sexual problems. The team will try different combinations of four automated components—education about sexual changes, training to talk with your clinician, training to talk with your partner, and activities to boost physical intimacy—using a factorial design to find the most helpful mix. About 320 women will be enrolled through community oncology sites in the NCI Community Oncology Research Program (NCORP) network, and the program is designed to lower time burden and reduce drop-out. Researchers will also look at who benefits most, why each piece works, and how people engage with the online tools.

Who could benefit from this research

Good fit: Intimately partnered women who have completed primary breast cancer treatment and report clinically significant sexual distress or dysfunction.

Not a fit: Unpartnered women, people still undergoing active cancer treatment, or those whose sexual issues are caused primarily by medical conditions rather than psychosocial factors may not benefit from this program.

Why it matters

Potential benefit: If successful, this could provide a tested, lower-burden online treatment that improves sexual well-being and relationships for breast cancer survivors.

How similar studies have performed: Previous online and psychosocial interventions for cancer-related sexual problems have shown promise but often faced high refusal or drop-out, and using the Multiphase Optimization Strategy to find the best component mix is a newer approach.

Where this research is happening

Charlottesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerBreast Cancer TreatmentBreast Cancer survivorCancer ControlCancer Control Science
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.