Better MRI Guidance for Children's Heart Procedures

Improved MRI guidance of pediatric catheterization via autonomous multi-beat data synthesis

NIH-funded research University of California, San Diego · NIH-11135321

This project aims to make MRI images clearer during heart catheterization procedures for children, offering a safer alternative to X-rays.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11135321 on NIH RePORTER

What this research studies

Heart catheterization is a way to check and fix heart problems without major surgery, but it usually uses X-rays, which expose children to radiation and don't show soft tissues very well. MRI is a safer option because it doesn't use radiation and provides better views of soft tissues. However, current real-time MRI images during these procedures can be blurry. Our goal is to develop new technology that combines information from multiple heartbeats to create much clearer, real-time MRI images, making these important procedures safer and more effective for young patients.

Who could benefit from this research

Good fit: This research is most relevant for children, particularly those aged 0-11 years, who need heart catheterization procedures for conditions like vascular stenosis or arrhythmias.

Not a fit: Patients who do not require heart catheterization or are not within the pediatric age range would not directly benefit from this specific advancement.

Why it matters

Potential benefit: If successful, this work could lead to safer and more precise heart catheterization procedures for children by reducing radiation exposure and improving image clarity.

How similar studies have performed: While MRI has guided some cardiac interventions in the past, improving real-time image quality during these procedures remains a significant challenge that this project aims to address with a novel approach.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.