Better MRI guidance for children's heart catheter procedures using automated multi-beat imaging

Improved MRI guidance of pediatric catheterization via autonomous multi-beat data synthesis

NIH-funded research University of California, San Diego · NIH-11374237

Using software that blends MRI data from multiple heartbeats to create clearer real-time images during catheter procedures for children.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11374237 on NIH RePORTER

What this research studies

This project will combine MRI data from several heartbeats with automated image-synthesis algorithms to produce clearer, real-time images during pediatric heart catheter procedures. The team plans to use low-field MRI and new processing methods to minimize device heating and improve soft-tissue contrast without X-ray radiation. Work includes developing the algorithms, testing image quality, and integrating the methods into clinical workflows for procedures. The goal is to make MRI-guided catheterizations faster, clearer, and safer for children with complex heart anatomy.

Who could benefit from this research

Good fit: Children who need heart catheterization—especially those with complex congenital heart anatomy or who require repeat procedures—would be the ideal candidates.

Not a fit: People who do not need catheterization or who cannot have an MRI (for example, due to incompatible implants or severe claustrophobia) are unlikely to benefit.

Why it matters

Potential benefit: Could make heart catheter procedures safer and more accurate for children by avoiding X-ray radiation and giving clearer images.

How similar studies have performed: Earlier first-in-human work showed MRI can guide some cardiac interventions, but real-time image quality has been limited and MRI guidance remains uncommon.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.