Better Lung Cancer Radiation Treatment with Personalized Motion Tracking

Personalized Motion Management for Truly 4D Lung Radiotherapy

NIH-funded research University of Maryland Baltimore · NIH-11132729

This project aims to improve radiation treatment for lung cancer by developing new ways to precisely track tumor movement caused by breathing.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Maryland Baltimore NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11132729 on NIH RePORTER

What this research studies

When patients receive radiation for lung cancer, tumors can move as they breathe, making it hard to deliver the exact dose needed. Current methods don't always capture this complex movement accurately, which can lead to less effective treatment or more side effects. This work focuses on creating a new, real-time system that combines advanced imaging techniques, 4DMRI and 4DCT, to build a personalized model of how a patient's tumor moves. This personalized approach helps doctors target the radiation more precisely, even as the patient breathes.

Who could benefit from this research

Good fit: This research is relevant for patients undergoing radiation therapy for lung cancer, particularly those whose tumors are affected by breathing motion.

Not a fit: Patients receiving radiation for cancers in areas not significantly impacted by respiratory motion, or those not undergoing radiation therapy, would not directly benefit from this specific advancement.

Why it matters

Potential benefit: If successful, this technology could lead to more accurate and effective radiation therapy for lung cancer patients, potentially reducing side effects and improving treatment outcomes.

How similar studies have performed: This project builds upon previous research in motion management, aiming to overcome limitations of existing strategies by developing a novel, more comprehensive approach.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.