Better lab tests to find colon and esophagus cancer earlier
Administrative Core-Biomarkers for optimizing risk prediction and early detection of cancers of the colon and esophagus
This program helps create and standardize clinical lab tests that could spot early signs of colon and esophagus cancer in people at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11167426 on NIH RePORTER |
What this research studies
The Administrative Core coordinates teams that discover potential biomarkers and turn promising findings into CLIA-compliant clinical assays. It supports validation work by Biomarker Discovery and Reference labs, and helps share data and protocols across clinical validation centers and industry partners. The core manages data review, quality control, and regulatory-ready assay development so tests can move from research toward real-world clinical use. Collaboration across centers aims to speed reliable tests into screening and diagnostic settings.
Who could benefit from this research
Good fit: People at elevated risk for colon or esophageal cancer or those undergoing screening or diagnostic evaluation would be the primary candidates for these tests and related validation studies.
Not a fit: Patients without risk for colon or esophageal disease or with unrelated conditions are unlikely to benefit directly from these specific biomarker assays.
Why it matters
Potential benefit: If successful, this work could produce reliable lab tests that detect colon and esophageal cancers earlier when treatment is more effective.
How similar studies have performed: Previous biomarker efforts have shown promise in some cases but often require rigorous validation, and this program builds on prior work to improve clinical readiness.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Grady, William Mallory — Fred Hutchinson Cancer Center
- Study coordinator: Grady, William Mallory
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.