Better Imaging for Brain Injury in Newborns
Imaging Neonatal Hypoxic Ischemic Injury
['FUNDING_R01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11122265
This project aims to create new imaging methods to understand brain damage in newborns who experience a lack of oxygen and blood flow, and how cooling treatments might help.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11122265 on ClinicalTrials.gov |
What this research studies
This project focuses on improving how we see brain damage in newborns who experience a lack of oxygen and blood flow, a condition called hypoxic ischemic injury. Researchers are creating advanced MRI techniques to look closely at brain tissue and how water moves within it, using a mouse model that mimics this injury in infants. These new imaging methods will help us understand how the injury progresses and how effective cooling treatments are at protecting the brain. The goal is to gain a deeper understanding of this condition and how treatments work, which could eventually lead to better care for affected babies.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but focuses on understanding a condition affecting newborns who experience hypoxic ischemic injury.
Not a fit: Patients not affected by neonatal hypoxic ischemic injury would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more precise ways to diagnose and monitor brain injury in newborns and improve understanding of how treatments like therapeutic hypothermia protect the brain.
How similar studies have performed: While animal models for neonatal HI injury are widely used, this project focuses on developing novel in vivo magnetic resonance imaging techniques, which represents an advancement in methodology.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHANG, JIANGYANG — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: ZHANG, JIANGYANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.