Better HIV and TB care for pregnant people, babies, children, and teens
IMPAACT Leadership Group
This network tests safer, longer-lasting HIV and TB treatments and ways to reduce or stop daily HIV medicines for pregnant people, infants, children, and adolescents.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11457800 on NIH RePORTER |
What this research studies
You would be part of a global research network that runs clinical trials and related studies for people with HIV and TB from pregnancy through adolescence. The teams try new antiretroviral drugs and dosing schedules, study how drugs behave in pregnant and young bodies and watch for safety, and test approaches aimed at HIV remission without daily treatment. They also develop and test better ways to prevent, diagnose, and treat TB in these groups. Studies are done at many clinical sites and can include drug dosing visits, sample collection, and medical follow-up.
Who could benefit from this research
Good fit: Ideal participants are pregnant or postpartum people, infants, children, and adolescents living with HIV or at high risk for TB who can attend study visits at participating sites.
Not a fit: People without HIV, those outside the specified age or pregnancy groups, or those unable to attend clinic visits are unlikely to benefit directly from enrolling.
Why it matters
Potential benefit: If successful, this work could lead to safer, easier-to-use HIV and TB treatments and strategies that let some people live without daily HIV pills.
How similar studies have performed: Previous maternal and pediatric HIV trials have produced safer dosing and new drug approvals, but efforts to reach ART-free remission and to optimize TB care in these groups remain relatively new and actively researched.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Nachman, Sharon a — Johns Hopkins University
- Study coordinator: Nachman, Sharon a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.