Better CT Scans with Sharper Images
Pixelated scintillators for ultra-high resolution cone-beam CT
This project is developing new technology to make CT scans much clearer, helping doctors see details more precisely for conditions affecting the brain, breast, and blood vessels.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11136969 on NIH RePORTER |
What this research studies
We are working on a new way to improve the 'scintillator' part of a CT scanner, which is responsible for converting X-rays into light that the machine can read. Currently, this part limits how sharp the images can be. Our approach involves creating tiny, separated pixels within the scintillator material to prevent light from spreading, which blurs the image. We will also use a special, denser material to ensure that even with these tiny pixels, the scanner still captures enough signal for a clear picture. This innovation aims to provide doctors with significantly more detailed images from CT scans.
Who could benefit from this research
Good fit: This technology development is not directly recruiting patients, but it aims to benefit adults who require high-resolution CT scans for conditions like brain issues, breast concerns, or blood vessel problems.
Not a fit: Patients who do not require advanced imaging or those undergoing basic diagnostic procedures may not directly experience the specific benefits of this ultra-high resolution technology.
Why it matters
Potential benefit: If successful, this technology could lead to earlier and more accurate diagnoses for various conditions, potentially improving treatment planning and outcomes for patients.
How similar studies have performed: While there have been advancements in other parts of CT scanners, this specific approach to pixelating and optimizing the scintillator material is a novel method to overcome current resolution limits.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Zbijewski, Wojciech Bartosz — Johns Hopkins University
- Study coordinator: Zbijewski, Wojciech Bartosz
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.