NIH-funded research R01 grant

Better control of below-elbow prosthetic hands using cloud tools and AI

Official title: Improved function performance in individuals with transradial limb difference using cloud based health system and deep learning

Funded at Rehabilitation Institute of Chicago D/b/a Shirley Ryan Abilitylab · NIH-11225165 · Data updated 2026-11-12

This project uses cloud-connected health tools and deep learning to help people with below-elbow amputations control myoelectric prosthetic hands more reliably.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRehabilitation Institute of Chicago D/b/a Shirley Ryan Abilitylab
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 20, 2014
Project endAugust 31, 2028
Funding year2025
Award (this year)$1,978,028
NIH project number2R01HD081525-06A1
Project IDNIH-11225165 on NIH RePORTER

Who could benefit from this research

Could help

Adults with transradial (below-elbow) limb loss who use or plan to use myoelectric prostheses and can attend clinic testing in Chicago are ideal candidates.

Less likely to help

People with amputations above the elbow, those who use only body-powered or purely cosmetic prostheses, or those unable to wear EMG sensors are unlikely to benefit.

What this research studies

If you have a below-elbow (transradial) amputation, this project aims to improve how your prosthetic reads muscle signals and responds to your intended movements. Researchers will compare a standard pattern-recognition controller to one enhanced with deep learning and data augmentation that can compensate for signal loss from loose electrodes or broken leads. A cloud-based system will collect device data, support recalibration, and enable controller updates during clinic and real-world use. The goal is fewer dropouts, easier recalibration, and better everyday function so people keep using their prostheses.

Why it matters

Potential benefit: Could make myoelectric prostheses more reliable and easier to use, improving daily function and reducing device abandonment.

How similar studies have gone: Prior studies show machine-learning methods can improve EMG control in lab settings, but combining deep learning with cloud-based augmentation for real-world prosthesis reliability is relatively new.

Where this research is happening

  • Rehabilitation Institute of Chicago D/b/a Shirley Ryan Abilitylab
    Chicago, United States
    Active

Researchers

  • Principal investigator: Hargrove, Levi John — Rehabilitation Institute of Chicago D/b/a Shirley Ryan Abilitylab
  • Study coordinator: Hargrove, Levi John

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.