Better cervical cancer screening and follow-up in Puerto Rico

The effectiveness, cost-effectiveness, and budget impact of interventions to improve the delivery of cervical cancer screening in Puerto Rico.

NIH-funded research Comprehensive Cancer Center/ Univ/pr · NIH-11184225

This project tries different approaches—like HPV self-sampling and patient navigators—to help more women in Puerto Rico get cervical cancer screening and timely follow-up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionComprehensive Cancer Center/ Univ/pr NIH-funded
Lab location1 site (San Juan, United States)
Project IDNIH-11184225 on NIH RePORTER

What this research studies

You would be invited through community and government clinics across Puerto Rico to join a randomized, four-arm trial comparing ways to improve screening. The trial compares HPV self-sampling at home, patient navigators who help overcome barriers and schedule follow-up, combined multicomponent approaches, and usual clinic care. Researchers will track who completes screening and follow-up care, and will collect data on costs and the budget impact for clinics. Findings will be used to recommend practical, affordable programs for government clinics serving low-income women.

Who could benefit from this research

Good fit: Ideal participants are women in Puerto Rico who are eligible for cervical cancer screening (roughly ages 21–65) who are overdue or under-screened, especially Medicaid or Medicare enrollees seen in government clinics.

Not a fit: People who are up-to-date with cervical screening, outside the eligible age range, or who have had a total hysterectomy for benign disease are unlikely to receive direct benefit from participation.

Why it matters

Potential benefit: If successful, this could increase timely screening and follow-up, lower late-stage cervical cancer diagnoses, and support affordable programs in Puerto Rico's clinics.

How similar studies have performed: HPV self-sampling and patient navigation have increased screening in other settings and early work in Puerto Rico shows self-sampling is acceptable, but full effectiveness and cost-effectiveness have not yet been demonstrated for this population.

Where this research is happening

San Juan, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions CancersCervical CancerCervical Cancer ScreeningCervix Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.