Better care for people with first-episode psychosis
Laboratory for Early Psychosis Research (LEAP)
A strengthened coordinated specialty care approach is being used to help people with a first episode of psychosis get better, faster treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mclean Hospital NIH-funded |
| Lab location | 1 site (Belmont, United States) |
| Project ID | NIH-11179451 on NIH RePORTER |
What this research studies
If I have a first episode of psychosis, this center connects me to coordinated specialty care clinics across Massachusetts and collects standardized clinical information about my care. The team will run a cluster randomized trial that compares an enhanced version of coordinated specialty care delivered across participating clinics. They will also combine clinic data with other sources and use modern prediction and comparative effectiveness methods to learn which treatments work best for different people. The center brings together clinicians, policy makers, and data scientists to turn those findings into improvements in routine care.
Who could benefit from this research
Good fit: People experiencing a first episode of psychosis who can attend participating coordinated specialty care clinics (primarily in Massachusetts) are ideal candidates.
Not a fit: People with long-standing or chronic psychotic disorders, or those unable to access participating clinics, may not receive direct benefit from this program.
Why it matters
Potential benefit: If successful, this work could help people with early psychosis get more effective, timely treatments and reduce long-term disability.
How similar studies have performed: Coordinated specialty care programs have previously improved outcomes for first-episode psychosis, but this enhanced, cluster-randomized approach combined with advanced prediction methods is relatively new.
Where this research is happening
Belmont, United States
- Mclean Hospital — Belmont, United States (Active)
Researchers
- Principal investigator: Ongur, Dost — Mclean Hospital
- Study coordinator: Ongur, Dost
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.