Better care and fairer outcomes for people with Crohn's disease and ulcerative colitis
RFA-DP-23-002, Improving Outcomes and Reducing Disparities for Patients with Inflammatory Bowel Disease through Epidemiology, Enhanced Disease Management, Dissemination, and Education
This program will test new management approaches and education to improve health and reduce disparities for teens and adults living with Crohn’s disease and ulcerative colitis.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11136211 on NIH RePORTER |
What this research studies
You would be part of a 52-week, open-label program run at multiple centers that enrolls 1,200 people aged 13 and older with inflammatory bowel disease (IBD). The project randomizes participants to different management strategies while following a prospective cohort drawn from the usual-care group to study how social risks influence IBD outcomes. Researchers will also develop and test patient- and provider-focused education and awareness activities created with input from patients and other stakeholders. The work is happening at six pediatric and five adult sites and combines epidemiology, practical care changes, and tailored education to try to improve equity and quality of life.
Who could benefit from this research
Good fit: Ideal candidates are people aged 13 and older with a diagnosis of Crohn’s disease or ulcerative colitis who can attend one of the participating pediatric or adult sites and follow study procedures for 52 weeks.
Not a fit: People without IBD, children under 13, or those unable or unwilling to travel to participating sites or complete study follow-up are unlikely to benefit from joining this program.
Why it matters
Potential benefit: If successful, this could improve quality of life and reduce health disparities for people with IBD by identifying effective care and education approaches.
How similar studies have performed: Previous programs addressing disease management and social determinants have improved outcomes in chronic conditions, but this large pragmatic trial combining epidemiology, management strategies, and stakeholder-informed education across ages is relatively novel.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Kappelman, Michael D — Univ of North Carolina Chapel Hill
- Study coordinator: Kappelman, Michael D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.