Better brain-controlled prosthetic arm for everyday tasks

Improved Brain-Computer Interface Decoding for Activities of Daily Life

NIH-funded research University of Chicago · NIH-11138724

Smarter brain-controlled arm and hand decoding for people with paralysis to help them use prosthetic limbs more smoothly for daily activities.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11138724 on NIH RePORTER

What this research studies

From my point of view, the team is building smarter ways to read brain signals so a prosthetic arm can move the arm and hand together instead of one after the other. They plan to use new algorithms that tap into more of the motor-cortex signals and pair those with more capable robotic hands that have better sensors. Tests will be done in the lab and with people who use or could use brain-controlled prostheses to practice real-life tasks. The goal is to make prosthetic use more reliable and flexible so everyday activities become easier.

Who could benefit from this research

Good fit: Adults with significant upper-limb paralysis who use or are candidates for brain-controlled prosthetic arms would be the ideal participants.

Not a fit: People without upper-limb paralysis or those who cannot undergo or do not want implantable BCI procedures are unlikely to benefit directly from this project.

Why it matters

Potential benefit: If successful, this work could allow people with paralysis to perform everyday tasks more naturally and reliably with a brain-controlled prosthetic arm.

How similar studies have performed: Previous BCI studies have achieved lab-based control of robotic arms and hands but have not yet delivered reliable, flexible use for everyday activities, so this work builds on partial successes.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.