Best time of day to exercise for heart and diabetes health

Timing of Physical Activity on Cardiometabolic Health Outcomes

NIH-funded research Brigham and Women's Hospital · NIH-11173811

This project looks at whether exercising at different times of day helps people with type 2 diabetes and heart risk factors get more benefit from physical activity.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11173811 on NIH RePORTER

What this research studies

From a patient's point of view, researchers will analyze week-long accelerometer records and health data from about 2,200 people with type 2 diabetes who took part in a previous lifestyle trial. They will compare when during the day people are active (morning, afternoon, evening) with measures like blood sugar, blood pressure, body fat, and other heart-related markers. The team will link activity timing to biological rhythms controlled by the body's internal clock to see if timing changes the benefits of exercise. Findings could point to clearer, time-based exercise advice for people with diabetes and cardiovascular risk.

Who could benefit from this research

Good fit: Adults with type 2 diabetes or people at elevated cardiovascular risk who are willing to share activity data or wear an activity monitor are most relevant to these findings.

Not a fit: People who cannot be physically active because of severe mobility or medical limitations, or whose health issues are unrelated to diabetes or cardiovascular risk, may not directly benefit from timing-based exercise guidance.

Why it matters

Potential benefit: If successful, this could lead to simple, time-based exercise guidance that improves blood sugar control and heart-health outcomes for people with type 2 diabetes.

How similar studies have performed: Animal studies and a few small human analyses suggest exercise timing can matter, but applying this idea to large cohorts with type 2 diabetes is relatively new and not yet proven.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes MellitusCardiovascular Diseases
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.