Beetroot Juice for Walking Difficulties in Peripheral Artery Disease

BEET root juice to reverse functional impairment in PAD: The BEET PAD Trial

NIH-funded research Northwestern University · NIH-11136505

This research explores if drinking beetroot juice can help people with peripheral artery disease walk better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11136505 on NIH RePORTER

What this research studies

People with peripheral artery disease (PAD) often experience difficulty walking due to reduced blood flow and damage to their calf muscles. This project aims to determine if beetroot juice, which is rich in a substance that can improve blood flow and muscle health, can help. We are conducting a large, multi-center study where participants with PAD will either drink beetroot juice or a placebo. Our main goal is to see if beetroot juice can significantly improve walking performance over four months by enhancing blood flow and muscle function in the legs.

Who could benefit from this research

Good fit: Ideal candidates are people diagnosed with lower extremity peripheral artery disease who experience functional impairment and walking difficulties.

Not a fit: Patients without peripheral artery disease or those whose walking difficulties stem from other conditions may not receive benefit from this specific approach.

Why it matters

Potential benefit: If successful, this could offer a simple, natural way to improve walking ability and overall mobility for people living with peripheral artery disease.

How similar studies have performed: Several small pilot studies, including some by the co-investigators, have shown promising results that beetroot juice may improve walking ability in people with PAD.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.