Bank of airway, blood, and brain cell samples for COVID and Long-COVID research
Core-003
This project collects and shares airway, blood, and brain cell samples from people with and without COVID-19 to help researchers find treatments for Long-COVID.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11517267 on NIH RePORTER |
What this research studies
The core collects primary human and mouse airway epithelial cells, immune and endothelial cells, and cells isolated from the brain, plus blood and fixed lung and brain tissues from people who had COVID-19 and from uninfected donors. Those samples are processed, maintained, and distributed to linked research projects to study which cell types and pathways drive inflammation and viral effects. By providing standardized, high-quality patient-derived samples, the core lets scientists compare infected and non-infected tissues and test potential therapeutic targets. The work supports several research projects within the program so findings can move more quickly toward possible therapies for Long-COVID.
Who could benefit from this research
Good fit: Ideal candidates include people who previously had COVID-19 (including those with persistent Long-COVID symptoms) as well as uninfected volunteers willing to donate blood, airway samples, or consent to tissue donation.
Not a fit: People seeking immediate medical treatment should not expect direct or immediate health benefits from participating, since the core primarily collects and shares samples for research.
Why it matters
Potential benefit: If successful, this resource could speed discovery of the cells and pathways that cause Long-COVID and point to new treatment targets.
How similar studies have performed: Other COVID biobanks and cell-based studies have successfully revealed immune pathways and candidate drug targets, so this sample-driven approach is established and promising.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Amer, Amal O — Ohio State University
- Study coordinator: Amer, Amal O
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.