NIH-funded research NIH-funded research

Avatar-led app using ACT to help young adults quit vaping

Official title: ACT on Vaping: Digital Therapeutic for Young Adult Vaping Cessation

Funded at Fred Hutchinson Cancer Center · NIH-11247482 · Data updated 2026-11-12

This project offers an avatar-led smartphone program based on Acceptance and Commitment Therapy to help young adults stop using e-cigarettes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionFred Hutchinson Cancer Center
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 15, 2022
Project endNovember 30, 2027
Funding year2026
Award (this year)$812,783
NIH project number5UH3DA057032-04
Project IDNIH-11247482 on NIH RePORTER

Who could benefit from this research

Could help

Young adults who currently use e-cigarettes and have a smartphone, including those at any stage of readiness to quit, are the intended participants.

Less likely to help

People who do not vape, who lack smartphone access, or who need immediate in-person medical treatment for nicotine dependence are unlikely to benefit from this app-based intervention.

What this research studies

You would use an avatar-led app that teaches Acceptance and Commitment Therapy (ACT) skills tailored for young adult vapers. The team will finish building the app, submit it for an FDA Q-review, and run a small randomized pilot comparing the app to brief advice and education. About 60 participants will be enrolled in the pilot with outcomes including self-report and biochemically confirmed abstinence. The goal is to check whether people like the app and show early signs of quitting before moving to a larger trial.

Why it matters

Potential benefit: If successful, this could give young adults an accessible digital tool that increases quit attempts and supports lasting vaping cessation.

How similar studies have gone: Previous pilot work of a similar ACT-based digital approach reported high user satisfaction and promising rates of biochemically confirmed tobacco abstinence, though larger trials are limited.

Where this research is happening

  • Fred Hutchinson Cancer Center
    Seattle, United States
    Active

Researchers

  • Principal investigator: Heffner, Jaimee — Fred Hutchinson Cancer Center
  • Study coordinator: Heffner, Jaimee

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.