Automatic screening for hip bone fragility using X-ray images
Official title: Automatic, Opportunistic Surveillance of Hip Bone Fragility in X-ray Images
Funded at Biosensics, LLC · NIH-10845548 · Data updated 2026-11-12
This study is working on a new software called XFx that helps doctors quickly check if older adults are at risk for hip fractures by looking at their X-ray images, making it easier and safer to spot potential problems without extra radiation.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biosensics, LLC NIH-funded |
| Lab location | 1 site (Newton, UNITED STATES) |
| Project start | June 1, 2023 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $918,848 |
| NIH project number | 5R44AG081031-02 |
| Project ID | NIH-10845548 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults, particularly those over the age of 50, who may be at risk for osteoporosis and fragility fractures.
✕Less likely to help
Patients who are younger than 50 or those without risk factors for osteoporosis may not benefit from this research.
What this research studies
This research aims to develop a cloud-based software called XFx that automatically screens for hip fracture risk by analyzing plain X-ray images. The software will allow healthcare providers to upload X-ray images, which will then be analyzed to assess bone geometry, microstructure, and density, all while minimizing exposure to ionizing radiation. By leveraging existing X-ray studies, this approach seeks to provide a cost-effective and accessible method for identifying patients at risk of fragility fractures, particularly in older adults. The project involves collaboration with experts in orthopaedics, radiology, endocrinology, and biomechanics to ensure comprehensive evaluation and validation of the software.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and intervention for patients at risk of hip fractures, potentially reducing morbidity and mortality associated with these injuries.
How similar studies have gone: Other research has shown promise in using imaging technologies for fracture risk assessment, indicating that this approach could be a meaningful advancement in the field.
Where this research is happening
-
Biosensics, LLC
Newton, United States Active
Researchers
- Principal investigator: Vaziri, Ashkan — Biosensics, LLC
- Study coordinator: Vaziri, Ashkan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.