Automated robots for treating dental biofilm infections

Small Scale Robotics for Automated Dental Biofilm Theranostics

NIH-funded research University of Pennsylvania · NIH-10840425

This study is exploring how tiny robots can help treat infections in your mouth by targeting stubborn areas that are hard to reach, making dental care easier and more effective for everyone.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10840425 on NIH RePORTER

What this research studies

This research focuses on developing small-scale robotic systems that can effectively target and treat oral biofilm-related infections, particularly in hard-to-reach areas like the endodontic canal systems. The approach combines nanotechnology and robotics, utilizing iron oxide nanoparticles to create robots that can kill and remove biofilms while also retrieving samples for diagnostics. By automating these processes, the research aims to improve the efficacy of dental treatments and reduce the need for manual interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from oral biofilm-related infections, particularly those with complex cases involving endodontic issues.

Not a fit: Patients without dental biofilm infections or those who do not require endodontic treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and less invasive treatments for dental biofilm infections, improving patient outcomes.

How similar studies have performed: Other research has shown promise in using robotic and nanotechnology approaches for medical applications, suggesting potential success for this novel method.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.