Automated PET tools to map how tracers spread in tumors
Automatic SUV Extraction and Biodistribution Analysis of Preclinical PET
This project builds a cloud tool that automatically finds organs and measures PET tracer uptake in animal cancer scans to speed imaging and drug research.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | In Vivo Analytics, INC. NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11195063 on NIH RePORTER |
What this research studies
Researchers are creating InVivoAX, a cloud-based system that automatically extracts organ regions from preclinical PET images and computes standardized uptake values and kinetic measures. They will pair the software with a Body Conforming Animal Mold (BCAM) to keep animals in consistent positions for better image alignment. The tool aims to remove operator bias, speed up co-registration between scans, and produce near-real-time biodistribution results. Overall, the approach combines automated image registration, ROI extraction, and rapid analytics to improve reproducibility and throughput in animal cancer imaging.
Who could benefit from this research
Good fit: This grant does not enroll people; it is focused on preclinical animal imaging studies used by researchers and labs developing cancer tracers and therapies.
Not a fit: Patients would not directly benefit from this project since it does not include human testing or patient enrollment.
Why it matters
Potential benefit: If successful, this could make preclinical imaging faster and more reliable, helping new cancer imaging agents and treatments move toward patients more quickly.
How similar studies have performed: Automated PET analysis and image-registration methods exist, but combining a body-conforming mold with cloud-based, near-real-time ROI extraction for preclinical biodistribution is a relatively novel and less-tested approach.
Where this research is happening
New York, United States
- In Vivo Analytics, INC. — New York, United States (Active)
Researchers
- Principal investigator: Klose, Alexander D. — In Vivo Analytics, INC.
- Study coordinator: Klose, Alexander D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.