NIH-funded research Sbir 2 grant

Automated feedback for student-made protein models using phones and AI

Official title: Harnessing Machine Learning & Object Detection for Automated Evaluation of Student-folded Protein Models

Funded at 3d Molecular Designs · NIH-11183303 · Data updated 2026-11-12

A smartphone app uses AI to give students and teachers immediate feedback on their student-made protein models created with flexible foam tools.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institution3d Molecular Designs
NIH-funded
Lab location1 site (Milwaukee, United States)
Project startAugust 1, 2024
Project endJuly 31, 2028
Funding year2026
Award (this year)$1,004,963
NIH project number2R44GM154526-02
Project IDNIH-11183303 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to patients; research focuses on educational tools for science learners and educators.

Less likely to help

This grant does not involve patients or patient care.

What this research studies

This project will develop and publish smartphone apps that use machine learning and object detection to analyze free-form protein models made by students. The goal is to provide real-time feedback on shape accuracy, secondary structures, and other features, helping educators guide learning more efficiently. The work combines education, software development, and AI imaging to support biology classrooms and outreach programs.

Why it matters

Potential benefit: If successful, students will receive fast, actionable feedback that can improve understanding of protein structure and science concepts.

How similar studies have gone: AI-based assessment and feedback for educational models is an emerging area with promising early results.

Where this research is happening

  • 3d Molecular Designs
    Milwaukee, United States
    Active

Researchers

  • Principal investigator: Ryan, Heather Noelle — 3d Molecular Designs
  • Study coordinator: Ryan, Heather Noelle

Related research

Other NIH-funded projects on the same topics.

  • Using machine learning to improve protein modeling education

    This study is all about making learning about proteins more fun and effective for students by using cool digital tools that give instant feedback on their protein models, helping them see and fix mistakes right away.

    NIH research 3d Molecular Designs · Milwaukee, United States · NIH-10918783

  • Preparing teachers for future pandemics through hands-on science education

    This study is all about helping high school science teachers learn more about infectious diseases and new technologies, so they can teach their students better using fun, hands-on tools like 3D-printed protein models.

    NIH research 3d Molecular Designs · Milwaukee, United States · NIH-10888284

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.