Automated device to measure DNA damage in cells
An automated device for quantifying DNA damage
['FUNDING_SBIR_2'] · ENGINEERING RESOURCES GROUP, INC. · NIH-11162483
This project is building a machine that measures DNA damage in cells to help spot risks tied to cancer, aging, and other diseases.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ENGINEERING RESOURCES GROUP, INC. (nih funded) |
| Locations | 1 site (PEMBROKE PINES, UNITED STATES) |
| Trial ID | NIH-11162483 on ClinicalTrials.gov |
What this research studies
From your perspective, the team is creating an automated version of the comet assay, a lab test that shows breaks and damage in DNA. The goal is to speed up testing, reduce hands-on steps, and cut errors that happen when slides are processed by hand. They developed a prototype in Phase I and are finishing a device that can run many samples more reliably for labs and regulators. If adopted, the device could make DNA damage testing more routine in research and clinical settings.
Who could benefit from this research
Good fit: Adults with conditions linked to genomic instability—such as certain cancers, neurodegenerative diseases, cardiovascular disease, or people with suspected exposure to DNA-damaging agents—could be candidates for future testing using this device.
Not a fit: People without concerns about DNA damage or those needing immediate treatment decisions are unlikely to get direct, timely benefit from this development project.
Why it matters
Potential benefit: If successful, this device could make DNA damage testing faster, cheaper, and more reliable, helping doctors and researchers detect exposure risks or monitor disease and treatments.
How similar studies have performed: The comet assay itself is a well-established laboratory method, but fully automated, high-throughput devices are relatively new and this project builds on earlier prototypes to bring automation to market.
Where this research is happening
PEMBROKE PINES, UNITED STATES
- ENGINEERING RESOURCES GROUP, INC. — PEMBROKE PINES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROSS, CHRISTOPHER — ENGINEERING RESOURCES GROUP, INC.
- Study coordinator: ROSS, CHRISTOPHER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.