Automated bedside blood monitor for sepsis and other critical illnesses
Automated Multiplex Analyzer for Sepsis and Beyond
A small device that automatically measures lactate, glucose, and hematocrit from a central line to help ICU patients get faster, less invasive monitoring.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cascade Metrix, LLC NIH-funded |
| Lab location | 1 site (Fishers, UNITED STATES) |
| Project ID | NIH-11256350 on NIH RePORTER |
What this research studies
If you are in the ICU with a central venous catheter, the AutoPlexer would attach to your line and automatically take tiny blood measurements without wasting blood. It measures lactate, glucose, and hematocrit frequently to help clinicians spot sepsis, acidosis, unstable blood sugar, or the need for transfusion sooner. The company developed and validated the device in preclinical pig models and is now refining the automated multiplex sampling for clinical use. The system is designed to reduce manual blood draws, avoid routine anticoagulant infusions, and speed result availability for bedside decision-making.
Who could benefit from this research
Good fit: Ideal candidates are hospitalized ICU patients who already have a central venous catheter and need frequent monitoring for sepsis, shock, trauma, or tight glycemic/hematocrit control.
Not a fit: Outpatients, people without a central venous catheter, or patients whose care does not require frequent blood monitoring are unlikely to benefit from this device.
Why it matters
Potential benefit: This could let care teams detect sepsis or metabolic problems earlier and reduce blood loss and manual needle sticks for ICU patients.
How similar studies have performed: Point-of-care blood tests are established, but automated in-line multiplex sampling like this has been validated in animal models with limited human testing so far.
Where this research is happening
Fishers, UNITED STATES
- Cascade Metrix, LLC — Fishers, United States (Active)
Researchers
- Principal investigator: Kunjan, Kislaya — Cascade Metrix, LLC
- Study coordinator: Kunjan, Kislaya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.